Sixteen samples showed a total absence of ABH antigens in both histologically normal and pathological areas. Results: In 31 of the 54 samples analyzed the test showed slightly positive results on atypical areas, and there was a complete antigen deletion in areas histologically affected by neoplasia. A strongly positive reaction was defined as a sheet of indicator erythrocytes adhered to the epithelia cells. Negative adherence was defined as a complete absence of adhered indicator erythrocytes. The test results were graded from negative adherence to very strongly positive adherence. Normal endothelial cells expressed ABH antigens, the presence of indicator erythrocytes at the lumen of the blood vessels served as a built in positive control. Study design: To reveal A, B and H antigens in tissue sections of patients with precancerous and cancerous oral lesions (n= 54) we used a modified specific red cell adherence technique (SRCA-test). Objectives: The aim of this work was to investigate the secretor status of patients with oral pre-cancerous and cancerous lesions and ABH antigens expression in fixed tissue sections of these patients. Facultad de Ciencias Bioquímicas y Farmacéuticas. (2) Laboratorio de Inmunohematología Histocompatibilidad e Inmunogenética. Secretor status and ABH antigens expression in patients with oral lesionsĬarlos Campi 1, Livia Escovich 1, Vanina Valdés 2, Silvia García Borrás 2, Liliana Racca 2, Amelia Racca 2, Carlos Cotorruelo 2, Claudia Biondi 2

Half life 2 abh